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T.原著論文 2.その他の生物活性物質

  1. 1) "Kobayashi K, Miyazawa S, Endo A. Isolation and inhibitory activity of gabaculine, a new potent inhibitor of γ-aminobutyrate aminotransferase produced by a Steptomyces. FEBS Lett 1977; 76: 207-210."
  2. 2) "Endo A, Kitahara N. cis and trans-Aconitic acids as inhibitors of glutamate decarboxylase. Hoppe-Seyler’s Z Physiol Chem 1977; 358: 1365-1368."
  3. 3) "Endo A, Kitahara N, Oka H, Miguchi-Fukazawa Y, Terahara A. Isoation of 4,5-dihydroxyisophthalic acid, an inhibitor of brain glutamate decarboxylase, produced by a streptomyces species. Eur J Biochem 1978; 82: 257-259."
  4. 4) "Endo A, Kitahara N. Inhibition of brain decardoxylase by 4,5-dihydroxyisophthalic acid and related compounds. J Antibiot 1981; 34: 1351-1354."
  5. 5) "Kitahara N, Endo A. Xanthocillin X monomethyl ether, a potent inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. J Antibiot 1981; 34: 1556-1561. "
  6. 6) "Kitahara N, Endo A, Furuya K, Takahashi S. Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricola. J Antibiot 1981; 34: 1562-1568."
  7. 7) "Sankawa U, Shibuya Y, Ebizuka Y, Noguchi H, Kinoshita Y, Iitaka Y, Endo A, Kitahara N. Depsids as potent inhibitors of prostaglandin biosynthesis: a new active site model for fatty acid cyclooxygenase. Prostaglandins 1982; 24: 21-34."
  8. 8) "Koga T, Hamada S, Murakawa S, Endo A. Effects of a glucosyltransferase inhibitor on glucan synthesis and cellular adlherence of Streptococcus mutans. Infect Immun 1982; 38: 822-886."
  9. 9) "Endo A, Hayashida O, Murakawa S. Mutastein, a new inhibitor of adhesive-insoluble glucan synthesis by glucosyltransferases of Streptococcus mutans. J Antibiot 1983; 36: 203-207."
  10. 10) " Nakamura Y, Kuwashima H, Endo A. Inhibitory effects of mutastein on carries development in rats infected with Streptococcus mutanns 6715. Jpn Oral Biol ( in Japanese) 1985; 27: 603-610."
  11. 11) "Endo A, Takeshima H, Kuwahara K. Acetyl-CoA carboxylase inhibitors from the fungus Congronella butreli. J Antibiot 1985; 38: 599-604."
  12. 12) "Endo A, Hasumi K, Sakai K, Kanbe T. Specific inhibition of glyceraldehyde-3-phosphate dehydrogenase by koningic acid (heptelidic acid). J Antibiot 1985; 38: 920-925."
  13. 13) "Takeshima H, Endo A, Wada K, Tanabe T. Inhibition of liver acetyl-coenzyme A carboxylase by 2-tetradecanylglutamate. J Antibiot 1986; 39: 275-280."
  14. 14) "Nakano Y, Murakawa S, Endo A. Inhibitory effect of mutastein on the synthesis of artificial dental plaque by Streptococcus mutans. J Antibiot 1987; 40: 227-229."
  15. 15) "Murakawa S, Tanabe N, Yamamoto F, Endo A. New fungal strains that produce a specific inhibitor of adhesive glucan synthesis Streptococcus mutans. J Antibiot 1987; 40: 394-395."
  16. 16) "Sakai K, Hasumi K, Endo A. Inactivation of rabbit muscle glyceraldehyde-3-phosphate dehydrogenase by koningic acid. Biochim Biophys Acta 1988; 952: 297-303."
  17. 17) "Sakai K, Hasumi K, Endo A. Two glyceradehyde-3-phosphate dehydrogenase isozymes from the konigic acid (heptelidic acid) producer Trichoderma koningii. Eur J Biochem 1990; 193: 195-202."
  18. 18) "Sakai K, Hasumi K, Endo, A. Identification of koningic acid (heptelidic acid)-modified site in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase. Biochim Biophys Acta 1991; 1077: 192-196."
  19. 19) "Woo JT, Miura S, Murakawa S, Endo A. Chrogalin, a heat-stable glycoprotein that inhibits polygalacturonase: isolation, characterization and biological activity. J Ferment Bioeng 1991; 72: 7-10."
  20. 20) "Kato M, Sakai K, Endo A. Konigic acid (heptelidic acid)-inhibition of glyceraldehyde-3-phosphate dehydrogenase from various sources. Biochim Biophys Acta 1992; 1120: 113-116."
  21. 21) "Kataoka T, Magae J, Kasamo K, Yamanishi H, Endo A, Yamasaki M, Nagai K. Effects of prodigiosin 25-C on cultured cell lines: its similarity to mono-valent polyether ionophores and vacuolar type H+-ATPase inhibitors. J Antibiot 1992; 45: 1618-1625."
  22. 22) "Watanabe H, Hasumi K, Fukushima Y, Sakai K, Endo A. Cloning of two isozymes of Trichoderma koningii glyceraldehyde-3-phoshate dehydrogenase with different sensitivity to koningic acid. Biochim Biophys Acta 1993; 1172: 43-48."
  23. 23) "Miura S, Hasumi K, Endo A. Inhibition of protein prenylation by patulin. FEBS Lett 1993; 318: 88-90."
  24. 24) "Kohyama T, Hasumi K, Endo A. Inhibition of 15-lipoxygenase by orobol. J Antibiot 1994; 47: 1069-1071."
  25. 25) "Inoue T, Hasumi K, Kuniyasu T, Endo, A. Isolation of plactins A, B, C and D,novel cyclic pentapeptides that stimulate cellular fibrinolytic activitty. J Antibiot 1996; 49: 45-49."
  26. 26) "Shinohara C, Hasumi K, Hatsumi W, Endo A. Staplabin, a novel fungal triprenyl phenol which stimulates the binding of plasminogen to fibrin and U9937 cells. J Antibiot 1996; 49: 961-966."
  27. 27) "Tachikawa K, Hasumi K, Endo A. Enhancemennt of plasminogen binding to U937 cells and fibrin by complestatin. Thromb Haemostat 1997; 77: 137-142."
  28. 28) "Chikanishi T, Hasumi K, Harada T, Kawasaki N, Endo, A. Clonostachin, a nove peptaibol that inhibits platelet aggregation. J Antibiot 1997; 50: 105-110."
  29. 29) "Kohyama T, Hasumi K, Hamanaka A, Endo A. SMTP-1 and ?2, novel analogs of staplabin produced by Stachybotrys microspora IFO 30018. J Antibiot 1997; 50: 172-174."
  30. 30) "Hayashida O, Hasumi K, Endo A. Chemical and functional properties of mutastein, an inhibitor of insoluble glucan synthesis by Streptococcus sorbinus. Biosci Biotech Biochem 1997; 61: 588-591."
  31. 31) "Hayashida O, Nakano Y, Hasumi K, Endo A. Inhibition of glucan synthesis by flavipin-crosslinked casein polymers. Biosci Biotech Biochem 1997; 61: 903-904."
  32. 32) "Sekiyama Y, Araya H, Hasumi K, Endo A, Fujimoto Y. Biosyntheisi of acaterin: isolation of 4,5-didehydroacaterin and its conversion into acaterin. Nat Prod Lett 1997; 11: 61-66."
  33. 33) "Tachikawa K, Hasumi K, Endo A. Enhancement of plasminogen binding and fibrinolysis by chloropeptin I. Thromb Res 1997; 87: 571-576."
  34. 34) "Takayasu R, Hasumi K, Shinohara C, Endo A. Enhancement of fibrin-binding and activation of plasminogen by staplabin thorugh an induction of a conformational change in plasminogen. FEBS Lett 1997; 418: 58-62."
  35. 35) "Inoue T, Hasumi K, Sugimoto M, Endo A. Enhancement of fibrinolysis by plactins: structure-activity relationship and effects in human U937 cells and in mice. Thromb Haemostat 1998; 79: 591-596."
  36. 36) "Hayashida O, Mori F, Hasumi K, Endo A. Inhibition of glucan synthesis by casein polymers crosslinked by glutaraldehyde. Biosci Biotech Biochem 1998; 62: 178-180."
  37. 37) "Miura S, Hasumi K, Takayasu R, Sugimoto M, Endo A. Enhancement of low density lipoprotein binding to both low density lipoprotein receptor-positive and-negative cells by tetracycline antibiotics. Lipids 1998; 33: 33-38."
  38. 38) "Sekiyama Y, Araya H, Hasumi K, Endo A, Fujimoto Y. Biosynthesis of acaterin: incorporation of glycerol into the C3 branched unit. Tetrahedron Lett 1998; 39: 6233-6236."
  39. 39) " Hasumi K, Ohyama S, Kohyama T, Ohsaki Y, Takayasu R, Endo A. Isolation of SMTP-3,-4,-5 and -6, novel analogs of staplabin, and their effects on plasminogen activation and fibrinolysis. J Antibiot 1998; 51: 1059-1068."
  40. 40) "Shinohara C, Hasumi K, Chikanishi T, Kikuchi T, Endo A. 11-Keto9(E), 12(E)-octadecadienoic acid, a novel fatty acid that enhances fibrinolytic activity of endothelial cells. J Antibiot 1999; 52: 171-174."
  41. 41) "Sekiyama Y, Fujimoto Y, Hasumi K, Endo A. Biosynthesis of acaterin: metabolic fate of sn-3 hydrogens of glycerol during the formation of 4-dehydroacaterin. Tetrahedron Lett 1999; 40: 4223-4226."
  42. 42) "Chikanishi T, Shinohara C, Kikuchi T, Endo A, Hasumi K. Inhibition of plasminogen activator inhibitor-1 by 11-keto-9(E), 12(E)-octadecadienoc acid, a novel fatty acid produced by Trichodema sp. J Antibiot 1999; 52: 797-802."
  43. 43) "Shinohara C, Chikanishi T, Nakashima S, Hashimoto A, Hamanaka A, Endo A, Hasumi K. Enhancement of fibrinolytic activity of vascular endothelial cells by chaetogloboisn A, crinipellin B, geodin and triticone B. J Antibiot 2000; 53: 262-268."
  44. 44) "Luo T, Fredericksen BL, Hasumi K, Endo A, Garcia JV. Human immunodeficiency virus type Nef-induced CD4 cell surface downregulation is inhibited by a novel antibiotic. J Virol 2001; 75: 2488-2492."
  45. 45) "Sekiyama Y, Fujimoto Y, Hasumi K, Endo A. Biosynthesis of acatrin: coupling of C5 unit with octanoate. J Org Chem 2001; 66: 5649-5654."
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