4-1．簡単な説明
膜結合酵素であるネズミチフス菌の細胞壁合成酵素の一つを精製して, 性質と作用機構を解明した（原著論文1-3、9, 11等, 総説・解説12, 14等）。2つの抗生物質（ポリオキシンＤとシッカニン）の作用機構等を解明した（原著論文4-8、10, 13等 ）。
4-2．原著論文(８編）と総説等（6編）
- 1) Endo A, Rothfield L. Studies of a phospholipid-requiring bacterial enzyme. I. Purification and properties of UDP-galactose : lipopolysaccharide-α3-galactosyl-transferase. Biochemistry 1969; 8: 3500-3507.
- 2) Endo A, Rothfield L. Studies of a phospholipid-requiring bacterial enzyme.Ⅱ. The role of phospholipid in the UDP-galactose:lipopolysaccharide-α3-galactosyl-transferase. Biochemistory 1969; 8: 3508-3515.
- 3) Rothfield L, Weiser M, Endo A. Dissociation and reassociation of bacterial membrane components. J Gen Physiol 1969; 54: 27s-37s.
- 4) Endo A, Misato T. Polyoxin D, a competitive inhibitor of UDP-N-acetyl- glucosamine:chitin N-acetylglucosaminyltransferase in Neurospora crassa.Biochem Biophys Res Commun 1969; 39: 718-722.
- 5) Endo A, Kakiki K, Hori M, Abe H, Misato T. A simple procedure for the preparation of UDP-N-acetylglucosamine-14C. Biochem Biophys Res Commun 1970; 39: 718-722.
- 6) Endo A, Kakiki K, Misato T. Feedback inhibition of L-glutamate D-fructose 6-phosphate amidotransferase by uridine diphosphate N-acetylglucosamine in Neurospora crassa. J Bacteriol 1970; 104: 189-196.
- 7) Endo A, Kakiki K, Misato T. Mechanism of action of the anifungal agent polyoxin D. J Bacteriol 1970; 105: 176-184.
- 8) Nose K, Endo A. Mode of acton of the antibioticsiccanin on the intact cells and mitochondria of Trichophyton mentagrophytes. J Bacteriol 1971; 105: 176- 184.
- 9) Rothfield L, Weiser M, Endo A. Dissociation and reassocication of bacterial membrane components. In: “Membrane Proteins”. New York Heart Association(ed), Little Brown & Co. Boston, 1969. pp.27-37.
- 10) Ishibashi K, Hirai K, Arai M, Sugawara S, Endo A. Siccanin, a new antifungal antibiotic. Ann Sankyo Res Labs 1970; 22: 1-33. Nose K, Endo A. Mode of action of the antibiotic siccanin on intact cells and mitochondria of Trichophyton mentagrophytes. J Bacteriol 1971; 105: 176-184.
- 11) 遠藤章. 細胞膜酵素の再構成. リポ多糖体合成酵素での研究. 蛋白質核酸酵素 1973; 18(9): 878-885.
- 12) 遠藤章. 生体膜酵素. 化学と生物 1973; 11(7): 414-421.
- 13) Tsujita Y, Endo A. The membrane-bound acid protease of Aspergillus oryzae: Its characterization and possible relation to the extracellular enzyme. Proc 1st International Congress of IAMS. Vol 5, Hasegawa, T (ed.), 1975. pp.176- 179.
- 14) 遠藤章. 膜結合酵素における脂質. 「生化学実験講座」 第9巻. 日本生化学会編, 東京化学同人, 1975. pp.496-500.
